April 6, 2012 Version 1.2.0-beta has been released, with a focus on performance increases. Read more
TIGER is a software platform for building and analyzing genome-scale models of metabolism. TIGER provides methods for combining gene-protein-reaction associations, transcriptional regulation, and other biological constraints into a single mixed-integer linear programming (MILP) framework. TIGER allows users to:
Parse and modify generalized Boolean and multilevel rules.
Convert logical rules into MILPs.
Develop integrated models of metabolism and gene-protein-reaction (GPR) relationships.
Add transcriptional regulatory rules to metabolic models.
Debug network models to find infeasible constraints.
Access MILP solvers through a platform-independent interface.